It is known that sialolithiasis is the most prevalent disease among salivary pathology. Based on different authors, it accounts for 20.5-78% of all cases. Even early detection of this disease doesn't guarantee the patient a complete recovery as the therapy of sialolithiasis, as a rule, is limited to surgical intervention (removal of the concrement or the salivary gland itself) without follow up impact on to the organ or the whole body. Quite frequently chronic inflammation of dystrophic process in the salivary gland after numerous cases of recurrence, becomes in indication to its removal . In many cases such outcome could have been prevented by administering adequate treatment, targeted at prevention of recurrence of salivary stone formation. Management of these issues formed the foundation of the work, defining is goals and objectives. Concrements mostly developed in submandibular (90-95%) and most rarely in parotis (5-8%). They were tested to establish chemical composition and the structure of such concrements in salivary glands, with the objective of identification of their development mechanisms. The total of 11 stones were removed from Wharton ducts of patients with sialolithiasis. Testing salivary stones yielded in following results: the major part of salivary stones (80%) consists of apatite and the remaining (20%) � of apatite and vitlocite. The prevention approach based on the mineral composition of stones had significantly reduced the formation of oxalatecalcium stones over three years. Nevertheless, it is desirable to continues such studies to confirms the efficiency of prevention of sialolithiasis by such method of treatment and collect more information on principles of action of such method.

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