SUMMARY The restrictive strabismus is the most frequent sequel in Thyroid Orbitopathy Objective. We want to determinate the effectiveness of botulinumToxin (botox) in correct restrictive strabismus and eliminate the diplopia in primary position of look and reading. Methods. we carried out a descriptive, prospective and longitudinal study to 10 patients (17 eyes) with restrictive strabismus of March to June of the 2008, using botulinum Toxin with direct method, without any electrical control, we have registered the effect and stability in strabismus and influence in the systemic disease. Results. BotulinumToxin?injection in the affected muscle was useful to correct restrictive strabismus and offers excellent results in the elimination of the diplopia and in the patients immediate comfort; we dont observe any influence in thyroid systemic diseases. The treatment can be to correct strabismus completely or waiting to go to surgery in a better moment. The botulinumToxin?s effectiveness could be for 4 to 6 months, but in some patients is for ever. We concludes that the therapeutic is a very good choice to treat strabismus not only for the efficacy but also for the safe and innocuous of the direct method of application

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