Abstract\r\nThe objective of this study was to assess gender differences in HIV/AIDS knowledge/awareness among university students at the University Nairobi, Kenya. The sample comprised 176 female and male participants randomly selected from 400 first and second year students registered for courses in the Department of Psychology. Participants were administered an HIV/AIDS questionnaire consisting of 15 statements/questions. The method of data analysis comprised frequencies, percentage and chi-square. The results showed a three-pronged pattern, where no gender differences were observed; where gender differences were clearly observed and where the level of knowledge for males and females was significantly different. Such performance was comparable to what other researchers have reported. In conclusion, the findings imply that awareness education methods may have to be separately designed with males and females in mind. In order to halt the rapid and wild spread of HIV/AIDS transmission, new strategies and approaches need to be put in place and administered with the gender differentials observed in this study.

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