Ponte Academic Journal Oct 2016, Volume 72, Issue 10 |
SOLITARY FIBROUS TUMOR OF THE LACRIMAL GLAND: A CLINICOPATHOLOGICAL REVIEW OF ALL REPORTED CASES IN COMPARISON TO THE SALIVARY GLAND AND A UNIQUE CASE REPORT SHOWING LACRIMAL GLAND ENTRAPMENT MIMICKING PLEOMORPHIC ADENOMA Author(s): Hind Manaa Alkatan ,Dr. Othman Jarallah Al Jarallah, Dr. Amany Abdulgader Fathaddin, Dr. Yasser H. Al-Faky J. Ponte - Oct 2016 - Volume 72 - Issue 10 doi: 10.21506/j.ponte.2016.10.30 Abstract: Purpose: Solitary fibrous tumor (SFT) is a rare tumor known to arise from the pleura. Extra pleural SFT has been described in the head and neck including the salivary glands and orbit. This research is based upon a collection of data from all reported cases of SFT in the lacrimal gland region in the English-written literature including our current case to provide useful baseline demographic as well as clinicopathological information concerning this tumor in the lacrimal gland in comparison to its counterpart in the parotid salivary gland.\\r\\nResults: All the information from 10 reported cases over the last 20 years, in addition to our current case, was carefully reviewed with focus on a specific histopathological finding of entrapped glandular tissue mimicking Pleomorphic adenoma. 11 cases were studied with detailed clinical information found in 9 out of the 11 cases. Age ranged from 24-76 years (mean=36 years). Male to female ratio was 2:1. Left orbit was involved in 7/9. A palpable mass was the commonest clinical presentation in 6/9, followed by upper lid swelling, proptosis and limited motility with a mean duration of 18 months. Histopathologically, 4 cases showed lacrimal gland tissue entrapment. Recurrence was noted in one case where the initial excision was misdiagnosed as Schwannoma.\\r\\nConclusions: SFT of the lacrimal gland -compared to the parotid gland- tends to occur at a younger age with stronger male predominance, and propensity for left side involvement. Duration of clinical presentation is shorter. The histopathological appearance including the entrapment of glandular tissue and the immunohistochemical features are similar in both locations. None of the lacrimal gland tumors showed atypical features.\\r\\n\\r\\n
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