The aim of this research is to study the role of free radical oxidation in the tissues of adrenal and immune organs and lymphocytes during combined effect of sublethal dose of gamma radiation (6 Gy) and coal-rock dust in remote period of time. Forty male Wistar rats were divided into four groups: I – control; II – exposure to coal-rock dust; III – exposure to radiation; IV – combined exposure of coal-rock dust and radiation. Rats from group III and IV exposed by radiation up to 90 days with 6 Gy once via Teragam Сo60 (Czech Republic). The analyses of lipid peroxidation indicators after the combined action of gamma radiation and coal-rock dust sublethal doses have been carried out. The combined effect was accompanied by the accumulation of products of diene conjugates and malonic dialdehyde lipids peroxidation in the homogenates. Moreover the development of dual oxidative stress in the investigated objects was observed. The enhanced content of lipid peroxidation products indicates that the increase of free radical processes is due to long term effect. The dominant role of ionizing radiation in combined exposure of coal-radiation factor has been revealed. Keywords: radiation, lipid peroxidation, coal-rock dust, combined action. Forty male Wistar rats were divided into four groups: I – control; II – exposure to coal-rock dust; III – exposure to radiation; IV – combined exposure of coal-rock dust and radiation. Rats from group III and IV exposed by radiation up to 90 days with 6 Gy once via Teragam Сo60 (Czech Republic). The analyses of lipid peroxidation indicators after the combined action of gamma radiation and coal-rock dust sublethal doses have been carried out. The combined effect was accompanied by the accumulation of products of diene conjugates and malonic dialdehyde lipids peroxidation in the homogenates. Moreover the development of dual oxidative stress in the investigated objects was observed. The enhanced content of lipid peroxidation products indicates that the increase of free radical processes is due to long term effect. The dominant role of ionizing radiation in combined exposure of coal-radiation factor has been revealed. Keywords: radiation, lipid peroxidation, coal-rock dust, combined action. Forty male Wistar rats were divided into four groups: I – control; II – exposure to coal-rock dust; III – exposure to radiation; IV – combined exposure of coal-rock dust and radiation. Rats from group III and IV exposed by radiation up to 90 days with 6 Gy once via TERAGAM Сo60 (Czech Republic). The analyses of lipid peroxidation indicators after the combined action of gamma radiation and coal-rock dust sublethal doses have been carried out. The combined effect was accompanied by the accumulation of products of diene conjugates and malonic dialdehyde lipids peroxidation in the homogenates. Moreover the development of dual oxidative stress in the investigated objects was observed. The enhanced content of lipid peroxidation products indicates that the increase of free radical processes is due to long term effect. The dominant role of ionizing radiation in combined exposure of coal-radiation factor has been revealed. Keywords: radiation, lipid peroxidation, coal-rock dust, combined action.

Username
Password