Levels of transaminase enzymes are influenced by environmental factors. These enzymes commonly measured as biomarkers for life health. The main aim of this study was to determine the effects of ultraviolet irradiations on serum levels of aspartate transaminase, alanine transaminase and alkaline phosphatase in Droshophyla melanogaster and was to evaluate the effect of water extract of propolis against UV treated D. melanogaster. Propolis biological activities have principally been attributed to its phenolic compounds, notable for significant antioxidant properties responsible for reducing the toxic effects of free radicals. UVA irradiation caused significant changes in both total soluble protein and transaminase enzymes as compared to control. The results indicated that level of aspartate transaminase has a significant decrease. Exposure to ultraviolet irradiations may lead to side effects. The data showed that propolis at 25 mg/ml concentrations exerted a certain influence on biochemical parameters studied. Treatment group (Propolis then UV irradiation) demonstrated the anticytotoxic properties of water extract of propolis on cross. The water extract of propolis exhibited protective effect against UVA irradiations. Poliphenols in propolis can reduce UV irradiation induced DNA damage.

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